The nonfermentable dietary fiber hydroxypropyl methylcellulose modulates intestinal microbiota
نویسندگان
چکیده
منابع مشابه
Hydroxypropyl methylcellulose in drug delivery
Hydroxy propyl methyl cellulose can be used in the development of different drug delivery technology. Nowadays it is a widely used polymer and different viscosity grade of this polymer is available. The hydrophilic and hydrophobic form (both variants) of this polymer is also available. This study includes a review of this polymer on use in different drug delivery system mosty focusing on more r...
متن کاملHydrophobically Modified Hydroxypropyl Methylcellulose in Rats
A six-month repeated-dose dermal toxicity study fo11owed by a 30-day recovery test of hydrophobically modified hydroxypropyl methylcellulose (HM-HPMC), a new ceLlulose derivative used as a thickener for topical pharmaceuticals, was conducted using rats, Aqueous paste of HM-HPMC was applied to the skin ofrats once daily at dose levels up to 60 mg/kglday, which was the highest dose that could be ...
متن کاملThe intestinal microbiota modulates the anticancer immune effects of cyclophosphamide.
Cyclophosphamide is one of several clinically important cancer drugs whose therapeutic efficacy is due in part to their ability to stimulate antitumor immune responses. Studying mouse models, we demonstrate that cyclophosphamide alters the composition of microbiota in the small intestine and induces the translocation of selected species of Gram-positive bacteria into secondary lymphoid organs. ...
متن کاملEffect of Functional Oligosaccharides and Ordinary Dietary Fiber on Intestinal Microbiota Diversity
Functional oligosaccharides, known as prebiotics, and ordinary dietary fiber have important roles in modulating the structure of intestinal microbiota. To investigate their effects on the intestinal microecosystem, three kinds of diets containing different prebiotics were used to feed mice for 3 weeks, as follows: GI (galacto-oligosaccharides and inulin), PF (polydextrose and insoluble dietary ...
متن کاملPupil size and reactivity following hydroxypropyl methylcellulose and sodium hyaluronate.
AIMS A prospective randomised clinical trial was set up to compare the effect of hydroxypropyl methylcellulose (Ocucoat) and sodium hyaluronate (Healonid) on pupil size and reactivity following their use in cataract surgery. METHODS Pupil measurements were recorded before and 6 weeks after surgery. RESULTS There was no significant difference between the two groups with respect to pupil size...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2012
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fj.12-219477